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Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

regenerating_mouse_retinal_ganglion_cell

Regenerating mouse retinal ganglion cell axons (magenta and green) extending from site of optic nerve injury (left). Photo courtesy of Andrew D. Huberman.

NIH-funded mouse study is the first to show that visual stimulation helps re-wire the visual system and partially restores sight.

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS) axons are capable of navigating to correct targets in the brain. The research was funded through the National Eye Institute (NEI), a part of NIH. Read More.

Published by National Eye Institute July 16, 2016


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