Researchers have identified a new target for the treatment of lymphoma and are testing a potential new drug in pet dogs afflicted with the disease. At low doses, the compound, called S-PAC-1, arrested the growth of tumors in three of six dogs tested and induced partial remission in a fourth.
Wednesday, September 8, 2010 - 15:03
Using high-resolution microscopy, researchers at the National Institutes of Health have shown how insulin prompts fat cells to take in glucose in a rat model. The findings were reported in the Sept. 8 issue of the journal Cell Metabolism.
Wednesday, September 8, 2010 - 11:44
A chemical that rid mice of malaria-causing parasites after a single oral dose may eventually become a new malaria drug if further tests in animals and people uphold the promise of early findings. The compound, NITD609, was developed by an international team of researchers including Elizabeth A. Winzeler, Ph.D., a grantee of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Friday, September 3, 2010 - 00:44
Here's good news for anyone trying to lose weight or has osteoporosis: Scientists from Maine are on the trail of a weight loss drug that may revolutionize how we treat these two conditions. In a new research report published in the September 2010 print issue of The FASEB Journal, the researchers describe a newly discovered protein, called "Sprouty," responsible for regulating body fat and bone mass.
Wednesday, September 1, 2010 - 12:46
Scientists from the National Institutes of Health and University of Chicago have found a promising treatment method that in laboratory mice reduces the severity of skin and soft-tissue damage caused by USA300, the leading cause of community-associated Staphylococcus aureus infections in the United States.
Wednesday, September 1, 2010 - 12:29
Current antiepileptic drugs (AEDs) have many side-effects, among others slowing down brain activity, which in turn reduces patients' ability to react. These side-effects could be eliminated if genes that counteract seizures could be introduced into the brain. Professor Merab Kokaia at Lund University in Sweden has obtained promising results in animal experiments.
Monday, August 30, 2010 - 11:14
We don't pay all that much attention to animal tests of experimental treatments. So many approaches that look good early on never make it in the real world. But, let's face it, when it comes to the deadly Ebola and Marburg viruses, you don't want to be testing the effectiveness of treatments in people for viruses that kill them 80 percent or more of the time.
Monday, August 30, 2010 - 10:58
Kissing a frog won't turn it into a prince — except in fairy tales — but frogs may be hopping toward a real-world transformation into princely allies in humanity's battle with antibiotic-resistant infections that threaten millions of people worldwide.
Friday, August 27, 2010 - 12:25
An international study led by biologists and neuroscientists from the University of Pennsylvania has identified a new genetic risk factor for amyotrophic lateral sclerosis, commonly known as ALS or Lou Gehrig’s disease.
Friday, August 27, 2010 - 12:13
A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms.
Thursday, August 19, 2010 - 12:45
Immature human nerve cells grew in the spines of injured mice and helped them walk a little better, researchers said on Wednesday in a study they said shows it may be possible to treat patients weeks or months after their accidents.
Thursday, August 19, 2010 - 11:48
In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision.
Tuesday, August 17, 2010 - 09:32
Hope that neural stem cells (NSCs) might be of benefit to individuals with severe spinal cord injury has now been provided by the work of a team of researchers, led by Kinichi Nakashima, at Nara Institute of Science and Technology, Japan, in a mouse model of this devastating condition.
Tuesday, August 17, 2010 - 09:28
Researchers for the first time have induced robust regeneration of nerve connections that control voluntary movement after spinal cord injury, showing the potential for new therapeutic approaches to paralysis and other motor function impairments.
Monday, August 9, 2010 - 09:27
Researchers supported by the National Institutes of Health have for the first time activated mouse egg cells at the earliest stage of their development and brought them to maturity. In a related experiment, the researchers replicated the finding by also bringing human eggs to maturity in the laboratory.
Wednesday, August 4, 2010 - 13:49
Researchers from the University of Sydney's Alzheimer's and Parkinson's Disease Laboratory have achieved a major breakthrough by finding the causes of Alzheimer's disease at a cellular level and thereby identifying a potential therapy as a result.
Wednesday, August 4, 2010 - 10:40
Multiple myeloma is one of the most common blood cancers, and at present considered to be incurable. In a new study from Uppsala University, researchers now present a conceptually new model for the development and progression of multiple myeloma.
Monday, August 2, 2010 - 11:01
Friday, July 30, 2010 - 11:31
A chemical compound that boosts the action of a molecule normally produced in the brain may provide the starting point for a new line of therapies for the treatment of epileptic seizures, according to a new study by scientists at The Scripps Research Institute.
Thursday, July 29, 2010 - 14:55
The experiment demonstrated the feasibility of an approach to growing dissimilar tissues, such as cartilage and bone, derived entirely from the host’s own cells. Results of the study are in the July 29 issue of The Lancet.
Thursday, July 29, 2010 - 09:43