A gene therapy technique which aims to ease memory problems linked to Alzheimer's Disease has been successfully tested in mice. US scientists used the technique to increase levels of a chemical which helps brain cells signal to each other.
Tuesday, November 30, 2010 - 12:33
Harvard scientists at Dana-Farber Cancer Institute say they have for the first time partially reversed age-related degeneration in mice, resulting in new growth of the brain and testes, improved fertility, and the return of a lost cognitive function.
Tuesday, November 30, 2010 - 12:24
Metformin, a drug used in type 2-diabetes might have the potential to also act against Alzheimer's disease. This has been shown in a study from scientists of the German Center for Neurodegenerative Diseases (DZNE), the University of Dundee and the Max-Planck-Institute for Molecular Genetics.
Wednesday, November 24, 2010 - 12:43
Researchers have found evidence that an environmental pollutant may play an important role in causing multiple sclerosis and that a hypertension drug might be used to treat the disease.
Wednesday, November 24, 2010 - 12:35
An old pinworm medicine is a new lead in the search for compounds that block a signaling pathway implicated in colon cancer. The findings, reported by Vanderbilt University Medical Center researchers in the November issue of Nature Chemical Biology, suggest a fresh approach for developing therapeutics that target the pathway.
Monday, November 22, 2010 - 14:46
New studies identify brain changes in people with Alzheimer's disease. The results give researchers a greater understanding of the disease and may help at-risk individuals by improving early detection.
Tuesday, November 16, 2010 - 21:04
New animal research has identified factors, such as the stress response and immune system, that may play important roles in depression. Scientists have also found that the regulation of nerve cell signals influences depression in animals, and that new drug combinations may more effectively treat it. The findings were presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health.
Tuesday, November 16, 2010 - 20:51
A drug used decades ago to treat high blood pressure has been shown to improve learning and memory in mouse models of Alzheimer’s disease, according to a new study by researchers at the National Institute on Aging (NIA), part of the National Institutes of Health.
Tuesday, November 16, 2010 - 13:05
There are disorders and conditions that entail increased itching and can be extremely troublesome for those suffering from it. The mechanisms behind itching are not well understood today. For one thing, what is it about scratching that relieves itching?
Friday, November 5, 2010 - 15:41
A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis (RA).
Wednesday, November 3, 2010 - 18:07
New research published in the Journal of Leukocyte Biology suggests that a purified form of a product modified from simple sugar molecules can eradicate killer viruses by mobilizing white blood cells.
Wednesday, November 3, 2010 - 18:01
A team of scientists from Japan and the University of California, San Diego School of Medicine have created a new mouse model that confirms that mutations of a protein called beta-synuclein promote neurodegeneration.
Wednesday, November 3, 2010 - 17:48
A molecular pathway within the brain’s reward circuitry appears to contribute to alcohol abuse, according to laboratory mouse research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The findings, published online today in Proceedings of the National Academy of Sciences, also provide evidence that the pathway may be a promising new target for the treatment of alcohol problems.
Tuesday, November 2, 2010 - 17:09
University scientists are using a seemingly unlikely animal to study development, cell function and the effects of debilitating human diseases. Ninety percent of zebrafish's amino acids are in the same order as a human's. Because of these similarities, zebrafish make excellent model organisms for research on human diseases.
Tuesday, November 2, 2010 - 17:01
At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team led by Sean Oldham, Ph.D., and Rolf Bodmer, Ph.D., recently created a simple model to link high-fat diet, obesity and heart dysfunction. Using fruit flies, they discovered that a protein called TOR influences fat accumulation in the heart.
Tuesday, November 2, 2010 - 16:15
Scientists at the National Institutes of Health have redefined the roles of several cytokines involved in the generation of immune cells implicated in severe autoimmune diseases. The study in mice showed that development of Th17 immune cells can occur without the presence of transforming growth factor (TGF)-beta, a mediator thought to be required for Th17 cell development.
Thursday, October 28, 2010 - 16:36
Genes involved in fruit fly learning processes are similar in structure and function to those in humans and other mammals.
Thursday, October 28, 2010 - 11:05
Type 1 diabetes (T1D), formerly known as juvenile diabetes, is a multifactorial disease of complex etiology characterized by the autoimmune destruction of pancreatic beta cells. In addition to genetic susceptibility, it is generally accepted that environmental factors play important roles in triggering disease, with virus infection having perhaps the strongest association.
Wednesday, October 27, 2010 - 14:12
Scientists are reporting progress in their efforts to channel brain waves to power mechanical devices, a development that could someday help paralyzed people regain mobility.
Wednesday, October 27, 2010 - 13:59
An operation commonly performed to remove brain tumors from the pituitary glands of humans is now available to dogs, thanks to a collaboration between a neurosurgeon and some veterinarians in Los Angeles. And that is turning out to be good for humans.
Monday, October 25, 2010 - 10:43