Researchers at the Johns Hopkins University School of Medicine have discovered that nitroxoline, an antibiotic commonly used around the world to treat urinary tract infections, can slow or stop the growth of human breast and bladder cancer cells by blocking the formation of new blood vessels. The results, appearing in the Dec. 15 issue of the Journal of the National Cancer Institute, suggest that nitroxoline shows promise as a potential therapeutic agent.
Tuesday, February 15, 2011 - 15:04
In new research from Saint Louis University, investigators have found evidence that a toxin produced by the brain is responsible for the series of cellular events that lead to Parkinson's disease. The study, published in PLoS One, found that the brain toxin DOPAL plays a key role in killing the dopamine neurons which trigger the illness.
Thursday, February 10, 2011 - 14:01
Although most people in developed countries get plenty of calories daily, their diets are often lacking in key nutrients that their bodies have evolved to expect. Omega-3 polyunsaturated fatty acids, such as those found in fish and walnuts, are one category of crucial ingredients that the body cannot make on its own.
Wednesday, February 2, 2011 - 13:16
A professor of veterinary medicine at the University of Missouri and his team have successfully performed a knee replacement procedure in dogs using biological cartilage. The cartilage was developed from the patient's own cells, which were grown in the lab and formed for insertion into the knee.
Monday, January 31, 2011 - 15:50
Biologists have grown beating heart cells directly from connective tissues in mice, skipping a previously required middle step -- the creation of stem cells.
Monday, January 31, 2011 - 15:39
After several years in the lab, researchers at City of Hope are reporting positive results in animal trials of a new treatment designed to both hunt down HIV-infected cells and stop the virus from spreading, according to a study published last week in the journal, "Science Translational Medicine."
Monday, January 24, 2011 - 12:39
MIT scientists have discovered that cells lining the blood vessels secrete molecules that suppress tumor growth and keep cancer cells from invading other tissues, a finding that could lead to a new way to treat cancer.
Thursday, January 20, 2011 - 15:20
Wed, Jan 19, 2011 — In a study published in the Cell Press journal Developmental Cell, a team of researchers led by Channing Der, PhD, Distinguished Professor of Pharmacology at UNC-Chapel Hill, took a step back to a simpler organism – a common roundworm – and made a discovery about how the Ras oncogene chooses a signaling pathway and how the consequences of that choice play out in cellular development – a key issue in cancer, which is characterized by uncontrolled cell growth.
Thursday, January 20, 2011 - 14:59
This molecule, a tiny strand of nucleotides called microRNA-29 or miR-29, has already been shown to be in short supply in certain neurodegenerative illnesses such as Alzheimer’s disease and Huntington’s disease.
Wednesday, January 19, 2011 - 12:30
The researchers found decreased formation of cell-to-cell connections, cell division and amounts of growth factors in the fetuses of mothers fed a reduced diet during the first half of pregnancy.
Wednesday, January 19, 2011 - 12:10
Massachusetts General Hospital (MGH) Cancer Center researchers have discovered a previously unknown feature of common tumor cells – massive overexpression of certain DNA sequences that do not code for proteins. These DNA sequences – called satellite repeats – have been studied for their role in chromosomal structure but previously were not suspected of having a role in cancer. The report will appear in the journal Science and is receiving early online release.
Friday, January 14, 2011 - 12:10
Research in rats suggests that "rebooting" the brain can help stop tinnitus, a condition characterized by persistent ringing or other noises in the ears.
Thursday, January 13, 2011 - 13:34
Using a mouse model, researchers have discovered that a molecular switch called EMMPRIN plays an important role in MS.
Wednesday, January 12, 2011 - 12:19
Australian and international researchers have announced a potential breakthrough in lung cancer research – linking it to a genetic mutation for which blocking drugs already exist.
Wednesday, January 12, 2011 - 12:00
A team of University of Missouri and Columbia University researchers have found a way to create these biological joints in animals, and they believe biological joint replacements for humans aren't far away.
Thursday, January 6, 2011 - 10:45
In a study published today in the Proceedings of the National Academy of Sciences (Early Edition ahead of print), a team of researchers from the Kennedy Krieger Institute and four collaborating institutions, identified a new and unexpected biological pathway that appears to contribute to the development of glaucoma and its resulting vision loss.
Tuesday, January 4, 2011 - 11:18
Friday, December 10, 2010 - 14:27
The American Physiological Society condemns all acts of violence or intimidation against individuals engaged in legitimate scientific inquiries intended to advance knowledge and improve health.
Friday, December 10, 2010 - 14:16
Stem cells taken from the brain of a 13-year-old girl were transplanted into newborn mice and developed into a variety of brain cells almost identical to the animals' own — a procedure that someday could be used to replace the misfiring cells in some epilepsy patients, the researchers said.
Wednesday, December 8, 2010 - 12:01
(SCHAUMBURG, Illinois) December 1, 2010—Citing its policy on the use of animals in research, testing and education, the American Veterinary Medical Association (AVMA) today condemned the recent actions of animal rights activists who have targeted a University of California research neuroscientist.
Wednesday, December 1, 2010 - 14:51