Wed, Jan 19, 2011 — In a study published in the Cell Press journal Developmental Cell, a team of researchers led by Channing Der, PhD, Distinguished Professor of Pharmacology at UNC-Chapel Hill, took a step back to a simpler organism – a common roundworm – and made a discovery about how the Ras oncogene chooses a signaling pathway and how the consequences of that choice play out in cellular development – a key issue in cancer, which is characterized by uncontrolled cell growth.
Thursday, January 20, 2011 - 13:59
This molecule, a tiny strand of nucleotides called microRNA-29 or miR-29, has already been shown to be in short supply in certain neurodegenerative illnesses such as Alzheimer’s disease and Huntington’s disease.
Wednesday, January 19, 2011 - 11:30
The researchers found decreased formation of cell-to-cell connections, cell division and amounts of growth factors in the fetuses of mothers fed a reduced diet during the first half of pregnancy.
Wednesday, January 19, 2011 - 11:10
Massachusetts General Hospital (MGH) Cancer Center researchers have discovered a previously unknown feature of common tumor cells – massive overexpression of certain DNA sequences that do not code for proteins. These DNA sequences – called satellite repeats – have been studied for their role in chromosomal structure but previously were not suspected of having a role in cancer. The report will appear in the journal Science and is receiving early online release.
Friday, January 14, 2011 - 11:10
Research in rats suggests that "rebooting" the brain can help stop tinnitus, a condition characterized by persistent ringing or other noises in the ears.
Thursday, January 13, 2011 - 12:34
Using a mouse model, researchers have discovered that a molecular switch called EMMPRIN plays an important role in MS.
Wednesday, January 12, 2011 - 11:19
Australian and international researchers have announced a potential breakthrough in lung cancer research – linking it to a genetic mutation for which blocking drugs already exist.
Wednesday, January 12, 2011 - 11:00
A team of University of Missouri and Columbia University researchers have found a way to create these biological joints in animals, and they believe biological joint replacements for humans aren't far away.
Thursday, January 6, 2011 - 09:45
In a study published today in the Proceedings of the National Academy of Sciences (Early Edition ahead of print), a team of researchers from the Kennedy Krieger Institute and four collaborating institutions, identified a new and unexpected biological pathway that appears to contribute to the development of glaucoma and its resulting vision loss.
Tuesday, January 4, 2011 - 10:18
Friday, December 10, 2010 - 13:27
The American Physiological Society condemns all acts of violence or intimidation against individuals engaged in legitimate scientific inquiries intended to advance knowledge and improve health.
Friday, December 10, 2010 - 13:16
Stem cells taken from the brain of a 13-year-old girl were transplanted into newborn mice and developed into a variety of brain cells almost identical to the animals' own — a procedure that someday could be used to replace the misfiring cells in some epilepsy patients, the researchers said.
Wednesday, December 8, 2010 - 11:01
(SCHAUMBURG, Illinois) December 1, 2010—Citing its policy on the use of animals in research, testing and education, the American Veterinary Medical Association (AVMA) today condemned the recent actions of animal rights activists who have targeted a University of California research neuroscientist.
Wednesday, December 1, 2010 - 13:51
A gene therapy technique which aims to ease memory problems linked to Alzheimer's Disease has been successfully tested in mice. US scientists used the technique to increase levels of a chemical which helps brain cells signal to each other.
Tuesday, November 30, 2010 - 11:33
Harvard scientists at Dana-Farber Cancer Institute say they have for the first time partially reversed age-related degeneration in mice, resulting in new growth of the brain and testes, improved fertility, and the return of a lost cognitive function.
Tuesday, November 30, 2010 - 11:24
Metformin, a drug used in type 2-diabetes might have the potential to also act against Alzheimer's disease. This has been shown in a study from scientists of the German Center for Neurodegenerative Diseases (DZNE), the University of Dundee and the Max-Planck-Institute for Molecular Genetics.
Wednesday, November 24, 2010 - 11:43
Researchers have found evidence that an environmental pollutant may play an important role in causing multiple sclerosis and that a hypertension drug might be used to treat the disease.
Wednesday, November 24, 2010 - 11:35
An old pinworm medicine is a new lead in the search for compounds that block a signaling pathway implicated in colon cancer. The findings, reported by Vanderbilt University Medical Center researchers in the November issue of Nature Chemical Biology, suggest a fresh approach for developing therapeutics that target the pathway.
Monday, November 22, 2010 - 13:46
New studies identify brain changes in people with Alzheimer's disease. The results give researchers a greater understanding of the disease and may help at-risk individuals by improving early detection.
Tuesday, November 16, 2010 - 20:04
New animal research has identified factors, such as the stress response and immune system, that may play important roles in depression. Scientists have also found that the regulation of nerve cell signals influences depression in animals, and that new drug combinations may more effectively treat it. The findings were presented at Neuroscience 2010, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news on brain science and health.
Tuesday, November 16, 2010 - 19:51