Cancer of the pancreas is usually not detected
until it’s too late to cure. But precursor lesions that form in the
pancreas and its ducts can signal the disease before it strikes, and
when caught early enough, they can be prevented from progressing to become cancer.
A new study reports two breakthroughs in understanding those lesions and their role in pancreatic cancer: the development of the first mouse model that simulates a precursor lesion called intraductal papillary mucinous neoplasia (IPMN), and the identification of an enzyme, Brg1, that appears to help cause the formation of IPMN lesions while also suppressing another precursor lesion.
Wednesday, February 26, 2014 - 15:58
Colorado State University researchers are finding new ways to treat cancers in humans and pets, but they are doing it with a specimen not of those species: mice.
Monday, February 24, 2014 - 15:28
There is no biological cure for deafness—yet. We detect sound using sensory cells sporting microscopic hairlike projections, and when these so-called hair cells deep inside the inner ear are destroyed by illness or loud noise, they are gone forever. Or so scientists thought. A new study finds specific cells in the inner ear of newborn mice that regenerate these sensory cells—even after damage, potentially opening up a way to treat deafness in humans.
Friday, February 21, 2014 - 14:08
A new potential test for persistent Lyme disease uses an organism that's known to be good at picking up diseases: ticks.
Wednesday, February 19, 2014 - 13:15
Here’s another reason to love a dog: our best friend is helping scientists identify the genetic variations that may lead to obsessive-compulsive disorder (OCD) in people, according to new research. Because the human and canine versions are often similar — dogs may lick their paws to the point of injury while people may wash their hands until they bleed — the hope is these and other findings will help researchers develop new medications to treat the debilitating disorder.
Tuesday, February 18, 2014 - 14:08
Japanese researchers have confirmed for the first time an association in mice between a genetic mutation and the intractable autoimmune disease lupus erythematosus.
Friday, February 14, 2014 - 13:58
Temporary blindness heightens hearing and has potential as a therapy for some deaf people, animal research suggests.
Thursday, February 6, 2014 - 15:28
Adult zebrafish can replace bones when they lose a tail fin. Knowing how they do it might lead to better ways to treat bone fractures in people, researchers say.
Friday, January 31, 2014 - 14:23
An Irish scientist is trying to unravel the secrets of what we smell and how our noses evolved to aid survival. And she has come up with important answers by studying the sniffing skills of the bat.
Thursday, January 30, 2014 - 14:10
A new study on worms with a genetic mutation could play a role in developing personalized diets for humans.
Wednesday, January 29, 2014 - 15:32
Dennis Kim, associate professor of biology at MIT, spends his days carefully raising worms that are no bigger than a comma. The students in his lab feed them, watching them grow and multiply on petri dishes that sit in a plastic tub.
Then they infect the worms with deadly bacteria and watch them fight for their lives.
But as the worms die, humans learn how the simplest immune system can stave off a deadly infection while swimming in a world of bacteria.
Thursday, January 23, 2014 - 15:32
A team of Yale researchers says it has found a genetic cause of Tourette syndrome, a discovery that could lead to better medications for the hard-to-treat disorder.
Friday, January 10, 2014 - 14:13
New research in mice suggests that a molecule linked to clogged arteries might activate the immune system to the point where it harms the body. The findings may explain why clogged arteries, a condition called atherosclerosis, have been tied to autoimmune disorders, which develop when the immune system goes awry.
"The lesson from this study is that immune diseases are not always a matter of immune system alone," said senior study author Yeonseok Chung, of the University of Texas Health Science Center at Houston. "With our findings, we have just started to understand how factors in the circulatory system impact the immune system."
Thursday, January 9, 2014 - 15:07
A faulty gene in mice may predispose some people with the same genetic defect to Type 2 diabetes, researchers at the University of Illinois at Chicago College of Medicine have found.
Tuesday, January 7, 2014 - 13:35
Congratulations to the naked mole rat, which was recently named the Vertebrate of the Year by Science Magazine! Naked mole rats have carved out a reputation for healthy living; they can last as long as 30 years and stay healthy right up to the end-and that includes never getting cancer.
Thursday, January 2, 2014 - 14:28
For all the weird and wonderful diversity of the animal kingdom, at the genetic level many species have a surprising level of similarity.
As a result we can learn a lot about the inner workings of our own human cells by studying other animals, and not all of them are mammals as you might expect.
Tuesday, December 31, 2013 - 14:00
The tropical zebrafish is the unlikely hero in providing hope for a different future for Charlie who has Duchenne Muscular Dystrophy (DMD).
Friday, December 20, 2013 - 14:53
New research by scientists in Germany - using a modified enzyme to kill HIV - is providing renewed hope that people living with the virus can be cured.
Thursday, December 19, 2013 - 15:41
A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.
Wednesday, December 18, 2013 - 15:11
On a recent visit to a laboratory where he researches obesity, Kevin Corbit walked over to one of the patients he is studying to say hello. Then he clasped a claw.
Dr. Corbit, a scientist at drug maker Amgen Inc., AMGN +0.38% is conducting his research on grizzly bears. He believes insights gleaned from the animals, who can take in as much as 58,000 calories in a day and weigh 1,000 pounds, could reshape understanding of obesity and identify new treatments for a condition that has stymied doctors and drug developers.
Monday, December 16, 2013 - 13:52