Scientists have good reasons to be curious about the genome of the naked mole-rat. The mole-rat, found in the deserts of East Africa, can survive many years in a harsh environment and appears to be resistant to diseases of aging, including cancer. Studies suggest that the mole-rat cells have anti-tumor characteristics not found in other rodents.
Thursday, July 7, 2011 - 10:36
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is a leading cause of cancer-related deaths worldwide. Although there are several treatment options available, they are largely unsuccessful because the disease is so poorly understood.
Wednesday, July 6, 2011 - 12:32
SALT LAKE CITY — Watch a life-saving drug flow into the arm of a loved one who has cancer or reach for prescription medication to ease your allergies or lower your blood pressure and there's a good chance you owe some thanks to a fruit fly, a zebrafish or a mouse. Or maybe all of them.
Wednesday, July 6, 2011 - 12:07
Scientists at the National Institutes of Health have uncovered a pathway in mice that allows white fat — a contributor to obesity and type 2 diabetes — to burn calories in a way that’s normally found in brown fat and muscle. The findings are in the July 6 edition of Cell Metabolism.
Wednesday, July 6, 2011 - 11:51
Long-term exposure to air pollution can lead to physical changes in the brain, as well as learning and memory problems and even depression, new research in mice suggests.
Tuesday, July 5, 2011 - 12:19
A protein previously thought not to exist in adult human lungs not only is present in normal and cancerous lung tissue, scientists have found, but it also has a major role in the development of a lethal complication of some lung cancers.
Tuesday, July 5, 2011 - 12:11
Stanford University School of Medicine investigators have linked a master molecule of the immune system, gamma-interferon, to the pathology of asthma, in a study of mice.
Tuesday, July 5, 2011 - 09:36
Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction. The work, conducted in rodent models, is the first to directly demonstrate the role of these specific connections in controlling behavior.
Friday, July 1, 2011 - 11:57
Rodent study identifies a key virus-sensing mechanism that is necessary for a successful immune response against infection with this particularly deadly type of virus. The research may help to guide the future design of more effective antiretroviral vaccines.
Thursday, June 30, 2011 - 13:44
In a U.S. study, early safety tests suggested the eggs of pig whipworms have anti-inflammatory properties, reducing the size of brain lesions in MS patients.
Thursday, June 30, 2011 - 13:26
For the first time, scientists have figured out how re-grow big chunks of human skeletal muscle by tricking the human body into accepting a biological matrix of pig proteins. If successful, this cellular regeneration method promises new life for injured war veterans and other trauma victims who are missing more than 25 percent of a limb and/or who face amputation.
Tuesday, June 28, 2011 - 12:26
Scientists have used a gene therapy tool that acts like intelligent molecular scissors to correct the key gene defect in mice with hemophilia B, a disease that can lead to uncontrolled bleeding. The intervention improved the animals’ blood clotting enough that their severe disease was reduced to a mild form.
Tuesday, June 28, 2011 - 12:19
Scientists have discovered the tool that bacteria normally found in our mouths use to invade heart tissue, causing a dangerous and sometimes lethal infection of the heart known as endocarditis.
Monday, June 27, 2011 - 11:11
Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson’s disease (PD) in a mouse model of the condition.
Friday, June 24, 2011 - 09:37
A study in mice has pinpointed a pivotal new player in triggering the rapid antidepressant response produced by ketamine. By deactivating a little-known enzyme, the drug takes the brakes off rapid synthesis of a key growth factor thought to lift depression, say researchers supported by the National Institutes of Health.
Thursday, June 23, 2011 - 12:46
A study led by researchers at the Joslin Diabetes Center suggests that adding the amino acid leucine to their diets may help those with pre-diabetes or metabolic syndrome.
Thursday, June 23, 2011 - 12:38
Initially the occurrence of progressive retinal degeneration - progressive retinal atrophy, in man called retinitis pigmentosa - had been identified in Schapendoes dogs.
Wednesday, June 22, 2011 - 10:07
Tuesday, June 21, 2011 - 09:44
In a study of mice, researchers have slowed an immune system attack on the ovaries. The mice developed a disorder resembling primary ovarian insufficiency (POI), a menopause-like condition that affects women under the age of 40, sometimes years or even decades before normal menopause.
Tuesday, June 21, 2011 - 09:17
Human organs could be grown inside pigs for use in transplant operations following research using stem cells.
Tuesday, June 21, 2011 - 09:11