Scientists have used a gene therapy tool that acts like intelligent molecular scissors to correct the key gene defect in mice with hemophilia B, a disease that can lead to uncontrolled bleeding. The intervention improved the animals’ blood clotting enough that their severe disease was reduced to a mild form.
Tuesday, June 28, 2011 - 12:19
Scientists have discovered the tool that bacteria normally found in our mouths use to invade heart tissue, causing a dangerous and sometimes lethal infection of the heart known as endocarditis.
Monday, June 27, 2011 - 11:11
Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson’s disease (PD) in a mouse model of the condition.
Friday, June 24, 2011 - 09:37
A study in mice has pinpointed a pivotal new player in triggering the rapid antidepressant response produced by ketamine. By deactivating a little-known enzyme, the drug takes the brakes off rapid synthesis of a key growth factor thought to lift depression, say researchers supported by the National Institutes of Health.
Thursday, June 23, 2011 - 12:46
A study led by researchers at the Joslin Diabetes Center suggests that adding the amino acid leucine to their diets may help those with pre-diabetes or metabolic syndrome.
Thursday, June 23, 2011 - 12:38
Initially the occurrence of progressive retinal degeneration - progressive retinal atrophy, in man called retinitis pigmentosa - had been identified in Schapendoes dogs.
Wednesday, June 22, 2011 - 10:07
Tuesday, June 21, 2011 - 09:44
In a study of mice, researchers have slowed an immune system attack on the ovaries. The mice developed a disorder resembling primary ovarian insufficiency (POI), a menopause-like condition that affects women under the age of 40, sometimes years or even decades before normal menopause.
Tuesday, June 21, 2011 - 09:17
Human organs could be grown inside pigs for use in transplant operations following research using stem cells.
Tuesday, June 21, 2011 - 09:11
Mayo Clinic investigators and collaborators from the United Kingdom cured well-established prostate tumors in mice using a human vaccine with no apparent side effects. This novel cancer treatment approach encourages the immune system to rid itself of prostate tumors without assistance from toxic chemotherapies and radiation treatments.
Monday, June 20, 2011 - 07:42
The findings suggest manipulating activity of PKD1, the gene causing the most common form of polycystic kidney disease, may prove beneficial in reducing cysts in both liver and kidney.
Monday, June 20, 2011 - 07:36
Scientists have designed a brain implant that restored lost memory function and strengthened recall of new information in laboratory rats — a crucial first step in the development of so-called neuroprosthetic devices to repair deficits from dementia, stroke and other brain injuries in humans.
Friday, June 17, 2011 - 11:48
Funded by the Defense Advanced Research Projects Agency (DARPA) and spurred by the return of injured Iraq and Afghanistan war veterans, researchers aim to design prostheses that will not only be able to move, but also provide amputees and quadriplegics with a sense of touch.
Friday, June 17, 2011 - 10:40
Scientists have figured out how ketamine works in the brain. In the process, they've uncovered a new molecular pathway involved in clinical depression.
Friday, June 17, 2011 - 07:34
Results of mouse research could eventually be used to treat people and prevent traumatic memories from taking over their lives — whether they are soldiers in combat or civilians caught up in a natural disaster.
Thursday, June 16, 2011 - 12:54
A dog diagnosed with a very aggressive form of cancer is beating the odds. He's alive today, thanks to some breakthrough cancer research by Oregon State University veterinarians.
Thursday, June 16, 2011 - 12:26
A study, conducted in baboon primates, finds that when mothers are even moderately undernourished while pregnant and breastfeeding, their offspring are consistently found to be prediabetic before adolescence. It is the first time that diabetes has been shown to have prenatal origins in a primate model.
Tuesday, June 14, 2011 - 08:29
There is an intimate and complex relationship between inflammation and cancer; and it is well established that tumors secrete many different chemicals that attract host cells which drive inflammation and help to support tumor growth. Now, a new study published by Cell Press in the June issue of the journal Cancer Cell identifies a single protein that is required for trafficking of immune cells involved in inflammation. The research opens up new avenues for therapeutics that can indirectly suppress malignancy by disrupting the inflammatory response.
Tuesday, June 14, 2011 - 08:23
In a mouse study, scientists at Mayo Clinic Florida have demonstrated the feasibility of a promising new strategy for treating human type 2 diabetes, which affects more than 200 million people worldwide.
Monday, June 13, 2011 - 09:48
In a new study published in the inaugural issue issue of the Journal of Parkinson's Disease, an international group of researchers report that platelet-derived growth factor-BB (PDGF-BB) restored function in rodents and shows promise as a clinical candidate drug for treatment of PD.
Thursday, June 9, 2011 - 11:49