Researchers studying the life threatening infectious disease sepsis have discovered how the infection can lead to a fatal inflammatory response through blood vessel cells. The research, which is published in EMBO Molecular Medicine, focuses on blocking crucial Matrix Metalloprotease enzymes (MMP) which activate the response.
Wednesday, May 18, 2011 - 09:57
Using a technique that silences genes promoting infection, researchers have developed a novel, topically-applied molecular microbicide capable of preventing HIV transmission. The microbicide is predicted to have long-lasting effects in mice, opening the door to developing an intravaginal microbicide that could protect women against HIV infection potentially for weeks at a time and bolster public health efforts to halt the spread of HIV/AIDS.
Tuesday, May 17, 2011 - 14:49
Scientists have identified a class of naturally occurring bacteria that can strongly inhibit malaria-causing parasites in Anopheles mosquitoes, a finding that could have implications for efforts to control malaria.
Monday, May 16, 2011 - 13:17
A new discovery in mice by researchers at Wake Forest Baptist Medical Center may one day allow doctors to spare some patients with acute myeloid leukemia (AML) from toxic treatments, while also opening the door for new therapeutic research.
Monday, May 16, 2011 - 12:41
In a study published this month, first author Budd A. Tucker said that he and principle investigator Michael J. Young took skin cells from the tails of rats and used chemical processes to turn them into “induced pluripotent stem cells,” then guided them into becoming precursor cells for retinal neurons.
Monday, May 16, 2011 - 11:07
New data offer hints to why Parkinson’s disease so selectively harms brain cells that produce the chemical dopamine, say researchers at Washington University School of Medicine in St. Louis.
Friday, May 13, 2011 - 11:02
For the first time, a vaccine has completely protected monkeys against infection with SIV, a virus related to HIV that infects the animals. Out of 24 immunised rhesus macaques, 12 had long-term protection, with no signs of SIV a year after they were deliberately infected with the virus.
Thursday, May 12, 2011 - 10:04
McGill research team found two distinct disease-causing mutations and saved a baby girl.
Wednesday, May 11, 2011 - 14:20
A common, tiny tropical fish plays a key role in a new model for Cushings disease, giving researchers a powerful tool to conduct extensive searches for effective treatments for this serious hormonal disorder, testing up to 300 drugs weekly.
Tuesday, May 10, 2011 - 10:07
Obesity appears to impair normal muscle function in rats, an observation that could have significant implications for humans, according to Penn State researchers. "Our findings demonstrate that obesity involves more than accumulating excess fat and carrying excess weight," said Rudolf J. Schilder, American Physiological Society postdoctoral fellow in physiological genomics, Penn State College of Medicine. "We show that, during the development of obesity, skeletal muscles fail to adjust their molecular composition appropriately to the increasing body weight. Consequently, the muscles of obese mammals are not properly 'tuned' to the higher body weight they carry."
Tuesday, May 10, 2011 - 09:57
University of Arkansas researchers found a way to use fat development in fruit flies to help understand fat metabolism in other animals, including humans. They have developed a genetic model to study a protein that regulates fat production and storage in fruit flies.
Monday, May 9, 2011 - 13:31
A team from the University of Minnesota Medical School and College of Veterinary Medicine successfully performed heart surgery for tetralogy of Fallot on Duke, a 2-year-old American Staffordshire terrier, at the Veterinary Medical Center on April 11.
Friday, May 6, 2011 - 11:43
Researchers looking for better ways to treat tumours in children say they may have stumbled instead on something even better - a new therapy for lung cancer, Australia's single biggest cancer killer.
Thursday, May 5, 2011 - 23:38
Research shows that the chemotherapy drug taxol (also called paclitaxel) could help improve recovery from spinal cord injuries. Writing in Science,* a team led by Frank Bradke, Ph.D., of the Max Planck Institute of Neurobiology in Martinsried, Germany reports that taxol helps repair spinal connections and improves walking in rats with spinal cord damage.
Thursday, May 5, 2011 - 23:33
Scientists have discovered why some people may be protected from harmful parasitic worms naturally while others cannot in what could lead to new therapies for up to one billion people worldwide.
Thursday, May 5, 2011 - 23:29
Scientists say they have found a way to turn body fat into a better type of fat that burns off calories and weight. The US Johns Hopkins team made the breakthrough in rats but believe the same could be done in humans, offering the hope of a new way to treat obesity.
Thursday, May 5, 2011 - 12:34
New protein regulates water in the brain to control inflammation.
Tuesday, May 3, 2011 - 14:02
Imagine a battlefield medic or emergency medical technician providing first aid with a special wad of cottony glass fibers that simultaneously slows bleeding, fights bacteria (and other sources of infection), stimulates the body's natural healing mechanisms, resists scarring, and—because it is quickly absorbed by surrounding tissue — may never have to be removed in follow-up care. Or, imagine diabetics with hard-to-heal wounds finding a source of relief from the battle against infections and limb amputation.
Tuesday, May 3, 2011 - 13:47
A gene therapy approach using a protein called CD59, or protectin, shows promise in slowing the signs of age-related macular degeneration (AMD), according to a new in vivo study by researchers at Tufts University School of Medicine.
Friday, April 29, 2011 - 14:39
Researchers have proven that melatonin –a natural hormone produced by the body– helps in controlling weight gain –even without reducing the intake of food–, improves blood lipid profile –as it reduces triglicerids–, increases HDL cholesterol and reduces LDL cholesterol.
Friday, April 29, 2011 - 10:28