In a new study published in the inaugural issue issue of the Journal of Parkinson's Disease, an international group of researchers report that platelet-derived growth factor-BB (PDGF-BB) restored function in rodents and shows promise as a clinical candidate drug for treatment of PD.
Thursday, June 9, 2011 - 12:49
Obesity among people who eat a high-fat diet may involve injury to neurons, or nerve cells, in a key part of the brain that controls body weight, according to the authors of a new animal study.
Thursday, June 9, 2011 - 11:45
British-based researchers claim they may be just a decade away from perfecting a way to persuade the heart to rejuvenate – a process thought to be impossible just five years ago.
Thursday, June 9, 2011 - 10:32
For Popeye, spinach was the key to extra muscle. For the mice in a new University of Iowa study, it was apples, or more precisely a waxy substance called ursolic acid that's found in apple peel.
Wednesday, June 8, 2011 - 14:17
The award-winning research, led by Professor Chris Shaw at Queen's School of Pharmacy, has identified two proteins, or ‘peptides’, which can be used in a controlled and targeted way to regulate 'angiogenesis' – the process by which blood vessels grow in the body.
Tuesday, June 7, 2011 - 11:04
Research from the University of Louisville published today (June 6) in the Proceedings of the National Academy of Sciences indicates the removal of a tiny RNA molecule in mice suppresses carcinogenic tumor formation.
Tuesday, June 7, 2011 - 10:54
Researchers at the Indiana University School of Medicine have discovered a peptide that short circuits a pathway for chronic pain. Unlike current treatments this peptide does not exhibit deleterious side effects such as reduced motor coordination, memory loss, or depression.
Monday, June 6, 2011 - 08:25
A study in a special early online publication of Cell, a Cell Press publication, reveals a promising new slow-release compound that protects mice against the neurodegenerative effects of both Huntington's and Alzheimer's disease. The 'prodrug' known only as JM6 works through a pathway involved in the breakdown of the amino acid tryptophan.
Friday, June 3, 2011 - 12:47
Eating a high-fat diet during pregnancy increases the chance of stillbirth, according to new research at Oregon Health & Science University. The new data show eating a typical American diet, which is high in fat, decreases blood flow from the mother to the placenta, the temporary organ that nourishes the unborn fetus.
Friday, June 3, 2011 - 12:40
Scientists at Dana-Farber Cancer Institute have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.
Thursday, June 2, 2011 - 11:37
A promising cancer treatment drug can restore function of a heart en route to failure from high blood pressure, researchers at UT Southwestern Medical Center have found.
Tuesday, May 31, 2011 - 11:46
A Californian team say they have managed to convert human skin cells directly into functioning brain cells. The scientists manipulated the process by which DNA is transcribed within foetal skin cells to create cells which behaved like neurons.
Friday, May 27, 2011 - 13:48
Studying the bloodless worm, C. elegans (pictured here), University of Maryland researchers have discovered a protein involved in the process by which humans, and other organisms safely move iron around in the body.
Thursday, May 26, 2011 - 14:11
Animal research is an important part of the research process when developing new treatments and medicines for patients.
Thursday, May 26, 2011 - 12:37
Scientists have found a way to get antibody-based therapies across a key barrier in the brain and deliver a payload of drugs that take aim at an elusive Alzheimer's target.
Thursday, May 26, 2011 - 11:02
After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer’s disease. The finding, reported in the June 14th issue of the Journal of Alzheimer’s Disease, offers a new target for drug development that could stave off the pathological disease process.
Wednesday, May 25, 2011 - 13:12
A cell treatment to prevent new organs being rejected without the need for lifelong courses of immune drugs is showing promise in mice and may one day make human transplants easier, scientists said.
Friday, May 20, 2011 - 13:51
Scientists at Fred Hutchinson Cancer Research Center have found that a protein called alpha-catenin acts as a tumor suppressor and they also have unlocked the mechanism by which this protein controls cell proliferation.
Friday, May 20, 2011 - 12:20
A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.
Thursday, May 19, 2011 - 11:40
About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds.
Wednesday, May 18, 2011 - 11:11