Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer's disease. The researchers' findings, published in the journal Science, show that use of a drug in mice appears to quickly reverse the pathological, cognitive and memory deficits caused by the onset of Alzheimer's. The results point to the significant potential that the medication, bexarotene, has to help the roughly 5.4 million Americans suffering from the progressive brain disease.
Friday, February 10, 2012 - 12:34
Researchers hoping to develop a promising new approach to treating cancer in people are trying it in another group: pet dogs. The aim of personalized medicine is to design an optimum cancer therapy after analyzing genes in a patient's tumor.
Tuesday, February 7, 2012 - 12:10
A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body's stem cells to travel to the surface of bones.
Monday, February 6, 2012 - 15:13
Scientists found that Gilenya, a drug recently approved in the US for treating MS, was effective at reversing the symptoms of ventricular hypertrophy in mice.
Tuesday, January 31, 2012 - 13:24
Leading Texas veterinarians are mobilizing to enlist pets in the testing of experimental cancer therapies, a potential benefit to not just dogs and cats but people.
Tuesday, January 31, 2012 - 13:11
Two women losing their sight to progressive forms of blindness may have regained some vision while participating in an experiment testing a treatment made from human embryonic stem cells, researchers reported today.
Thursday, January 26, 2012 - 13:32
Scientists now have a better understanding of the way that stress impacts the brain. New research, published by Cell Press in the January 26 issue of the journal Neuron, reveals pioneering evidence for a new mechanism of stress adaptation and may eventually lead to a better understanding of why prolonged and repeated exposure to stress can lead to anxiety disorders and depression.
Thursday, January 26, 2012 - 13:00
Four years ago, teams of researchers at the University of Pennsylvania and elsewhere made headlines by restoring some sight to blind people, though it was a form of blindness few had heard of.
Wednesday, January 25, 2012 - 14:05
Dogs with spinal cord injuries may soon benefit from an experimental drug being tested by researchers at the University of California, San Francisco (UCSF) and Texas A&M College of Veterinary Medicine & Biomedical Sciences — work that they hope will one day help people with similar injuries.
Thursday, January 19, 2012 - 15:10
A fountain of youthful cells reverses the damage found in diseases like multiple sclerosis, a study in mice reveals.
Tuesday, January 17, 2012 - 15:23
Researchers have discovered that planarians, a type of flatworm that easily regenerates, do not contain centrosomes within their cells, a structure present in the cells of every other known living animal.
Tuesday, January 17, 2012 - 13:58
A recent study in mice found that the gastrointestinal parasite Nippostrongylus brasiliensis induces the immune system to produce wound-healing substances. Helminthic therapy, or the use of parasites to combat diseases of the immune system, has been studied for years using the pig parasite Trichuris suis to treat inflammatory diseases, but this study is the first to find the wound-healing byproducts of parasitic infection. Scientists hope to use that information to treat human ailments.
Tuesday, January 17, 2012 - 13:55
Inflammation is correctly blamed as one of the root causes of both acute and chronic pain—and more. Not only does chronic inflammation underlie disorders such as rheumatoid arthritis, inflammatory bowel disease, and other autoimmune diseases, it has also been implicated in the pathogenesis of cancer, chronic heart failure, and neurological disorders such as Parkinson’s and Alzheimer’s diseases.
Thursday, January 12, 2012 - 13:40
Combination drug treatment that targets estrogen production significantly reduced the number of tobacco carcinogen-related lung tumors in mice, a new study shows.
Tuesday, January 10, 2012 - 16:48
In humans, active periods of the debilitating disease Multiple Sclerosis (MS) can last for mere minutes or extend to weeks at a time. They're caused by lesions in the brain that develop, partly heal, and then recur. Research into a cure has been difficult, because to date scientists have not been able to replicate these brain recurring symptoms in laboratory mice. That's frustrating because these lab animals, known as animal "models," are the primary tool for research into the mechanisms and potential treatments for MS.
Friday, January 6, 2012 - 11:51
New vaccine research in monkeys suggests that scientists are homing in on the critical ingredients of a protective HIV vaccine and identifies new HIV vaccine candidates to test in human clinical trials.
Friday, January 6, 2012 - 11:41
Newly published research by scientists at Oregon Health & Science University provides significant new information about how early embryonic stem cells develop and take part in formation of the primate species. The research, which took place at OHSU's Oregon National Primate Research Center, has also resulted in the first successful birth of chimeric monkeys.
Thursday, January 5, 2012 - 14:50
Human adenoviruses have been proposed as vectors for antigens in vaccines because of their ability to induce strong immune responses in animal models. But there is one major problem—patients that have already been exposed to such adenoviruses naturally develop antibodies against them, which then neutralize the vaccine before it has a chance to deliver its package.
Thursday, January 5, 2012 - 11:45
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida’s Department of Psychiatry and the Silver Child Development Center.
Thursday, January 5, 2012 - 11:34
Researchers are beginning to understand why lasting weight loss is so hard. They believe it has to do with damage to the part of the brain that’s involved in weight control.
Wednesday, January 4, 2012 - 13:34