In humans, active periods of the debilitating disease Multiple Sclerosis (MS) can last for mere minutes or extend to weeks at a time. They're caused by lesions in the brain that develop, partly heal, and then recur. Research into a cure has been difficult, because to date scientists have not been able to replicate these brain recurring symptoms in laboratory mice. That's frustrating because these lab animals, known as animal "models," are the primary tool for research into the mechanisms and potential treatments for MS.
Friday, January 6, 2012 - 11:51
New vaccine research in monkeys suggests that scientists are homing in on the critical ingredients of a protective HIV vaccine and identifies new HIV vaccine candidates to test in human clinical trials.
Friday, January 6, 2012 - 11:41
Newly published research by scientists at Oregon Health & Science University provides significant new information about how early embryonic stem cells develop and take part in formation of the primate species. The research, which took place at OHSU's Oregon National Primate Research Center, has also resulted in the first successful birth of chimeric monkeys.
Thursday, January 5, 2012 - 14:50
Human adenoviruses have been proposed as vectors for antigens in vaccines because of their ability to induce strong immune responses in animal models. But there is one major problem—patients that have already been exposed to such adenoviruses naturally develop antibodies against them, which then neutralize the vaccine before it has a chance to deliver its package.
Thursday, January 5, 2012 - 11:45
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida’s Department of Psychiatry and the Silver Child Development Center.
Thursday, January 5, 2012 - 11:34
Researchers are beginning to understand why lasting weight loss is so hard. They believe it has to do with damage to the part of the brain that’s involved in weight control.
Wednesday, January 4, 2012 - 13:34
A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, researchers say.
Tuesday, January 3, 2012 - 13:14
Working with mice, scientists at Johns Hopkins have successfully used a commonly prescribed blood pressure medicine, losartan (Cozaar), to prevent almost all of the lung damage caused from two months of exposure to cigarette smoke. The treatment specifically targeted lung tissue breakdown, airway wall thickening, inflammation and lung over-expansion.
Tuesday, January 3, 2012 - 12:11
New research by scientists at The Scripps Research Institute has underlined the power of an endogenous anti-stress peptide in the brain to prevent and even reverse some of the cellular effects of acute alcohol and alcohol dependence in animal models. The work could lead to the development of novel drugs to treat alcoholism.
Friday, December 30, 2011 - 13:29
Working with guinea pigs, tuberculosis experts at Johns Hopkins and elsewhere have closely mimicked how active but untreated cases of the underlying lung infection lead to permanent eye damage and blindness in people.
Thursday, December 29, 2011 - 13:45
A synthetic vaccine based on nanotechnology holds out the promise of halting autoimmune diseases such as Crohn's and rheumatoid arthritis, it has been reported. Early research has shown that the molecular principle behind the approach works, at least in mice.
Wednesday, December 28, 2011 - 14:58
Acupuncture significantly reduces levels of a protein in rats linked to chronic stress, researchers at Georgetown University Medical Center (GUMC) have found. They say their animal study may help explain the sense of wellbeing that many people receive from this ancient Chinese therapy.
Wednesday, December 21, 2011 - 13:48
Wednesday, December 21, 2011 - 13:29
Stabilizing the cell’s power-generating center protects against Parkinson’s disease (PD) in a rat model, according to a report published online this week in the Journal of Experimental Medicine
Tuesday, December 20, 2011 - 14:23
A new drug candidate may be the first capable of halting the devastating mental decline of Alzheimer's disease, based on the findings of a study published in PLoS ONE.
Thursday, December 15, 2011 - 14:25
Neuroscience researchers from Tufts have demonstrated, for the first time, that the physiological response to stress depends on neurosteroids acting on specific receptors in the brain, and they have been able to block that response in mice.
Wednesday, December 14, 2011 - 13:12
Johns Hopkins researchers have developed a jelly-like material and wound treatment method that, in early experiments on skin damaged by severe burns, appeared to regenerate healthy, scar-free tissue.
Wednesday, December 14, 2011 - 13:00
The vaccine, described this week in the early edition of the journal Proceedings of the National Academy of Sciences, reveals a promising new strategy for treating cancers that share the same distinct carbohydrate signature, including ovarian and colorectal cancers.
Tuesday, December 13, 2011 - 11:30
A transparent cornea is essential for vision, which is why the eye has evolved to nourish the cornea without blood vessels. But for millions of people around the world, diseases of the eye or trauma spur the growth of blood vessels and can cause blindness.
Tuesday, December 13, 2011 - 11:16
According to cost analysis for the legislation compiled by the Humane Society of the United States, the majority of cost-savings from GAPA – 76% – would result from ending federal grants for projects involving chimpanzees. Of the “nearly $30 million saved annually” over $22 million reflects funds committed to support research projects that involve chimpanzees and are funded by the National Institutes of Health (NIH).
Thursday, December 8, 2011 - 15:12