A landmark study in mice identifies a biological mechanism that could help explain how tobacco products could act as gateway drugs, increasing a person's future likelihood of abusing cocaine and perhaps other drugs as well, according to the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. The study is the first to show that nicotine might prime the brain to enhance the behavioral effects of cocaine.
Friday, November 4, 2011 - 09:40
A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease.
Wednesday, November 2, 2011 - 12:39
Can the nerve signaling inhibitor tomosyn help retain long-term memory? A new study by two University of Illinois at Chicago biologists points to the link.
Tuesday, November 1, 2011 - 12:10
A new therapy being studied in non-human primates by researchers at Wake Forest Baptist Medical Center and colleagues is demonstrating promise as a potential tool for combating cardiovascular disease by increasing good cholesterol and lowering triglycerides in the blood. Supported by the National Institutes of Health and the Canadian Institutes of Health Research, the preclinical findings appear in this week’s issue of the journal Nature.
Monday, October 31, 2011 - 13:20
Salmon, a natural source of omega-3. Professor Breier, who leads an international research team, says omega-3s are especially beneficial for health in ageing because they improve carbohydrate and fat metabolism. His research found a diet high in omega-3 fatty acids helps to burn metabolic fuels (glucose and fat) better, and can regulate energy storage across different tissues.
Monday, October 31, 2011 - 12:49
In a development that sheds new light on the pathology of Alzheimer’s disease (AD), a team of Whitehead Institute scientists has identified connections between genetic risk factors for the disease and the effects of a peptide toxic to nerve cells in the brains of AD patients.
Friday, October 28, 2011 - 14:29
Pythons are known for their enormous appetites. In a single meal they can devour animals at least as big as they are — deer, alligators pigs and house pets, for example. Equally remarkable is what happens inside the python as it digests its prey.
Friday, October 28, 2011 - 14:18
The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that go haywire in melanoma, as well as in more common conditions as vitiligo and albinism.Naturally, researchers would love to study melanocytes in the laboratory. There's just one problem -- melanocytes from adult skin don't grow very well in the lab.
Thursday, October 27, 2011 - 13:51
Thursday, October 27, 2011 - 12:20
Animal experiments in the UK are on the rise. Though controversial, these tests are transforming human lives, discovers Paul Vallely.
Tuesday, October 25, 2011 - 12:21
Rats exposed to an antidepressant just before and after birth showed substantial brain abnormalities and behaviors, in a study funded by the National Institutes of Health.
Tuesday, October 25, 2011 - 11:37
“Estrogen has a profound effect on metabolism,” said Dr. Deborah Clegg, associate professor of internal medicine and senior author of the study published Oct. 5 in Cell Metabolism. “We hadn’t previously thought of sex hormones as being critical regulators of food intake and body weight.”
Friday, October 21, 2011 - 10:29
Researchers at Emory University School of Medicine have identified a set of genes that act in muscles to modulate aging and resistance to stress in fruit flies.
Tuesday, October 18, 2011 - 10:34
Sickle cell anemia is a genetic disease that affects hemoglobin production. It is estimated that as many as 100,000 people in the United States and many more in other parts of the world, Africa in particular, have the disease.
Monday, October 17, 2011 - 15:01
A team of researchers led by the Sanger Institute and the University of Cambridge used cutting-edge methods to correct a genetic mutation in stem cells derived from a patient's skin biopsy, and then grew them into fresh liver cells.
Friday, October 14, 2011 - 14:35
Modern medicine’s ability to save lives through organ transplantation has been revolutionized by the development of drugs that prevent the human body from rejecting the transplanted organ. But those antirejection drugs have their own side effects — sometimes serious.
Tuesday, October 11, 2011 - 12:10
Scientists in the US were able to normalise blood sugar levels in diabetic mice by injecting them with a compound, nicotinamide mononucleotide (NMN). At the same time the jabs lowered raised levels of cholesterol and triglyceride blood fats.
Tuesday, October 11, 2011 - 12:01
University of Alabama scientist Harald Sontheimer has become popular with brain cancer patients and their doctors after his ongoing research found that a drug approved to treat Crohn's disease in humans shrinks brain tumors in mice.
Tuesday, October 11, 2011 - 11:48
Over the next five years, National Institutes of Health (NIH)-funded researchers will extensively test and generate data about mice with disrupted genes to gain clues about human diseases. NIH today awarded a set of cooperative agreements totaling more than $110 million to begin the second phase of the Knockout Mouse Project (KOMP).
Thursday, September 29, 2011 - 11:11
Ralph Brinster, a prominent veterinary scientist at the University of Pennsylvania, is to receive the National Medal of Science for his work on transgenic lab animals - research that helped lay the foundation for much of modern biomedicine.
Thursday, September 29, 2011 - 10:52