Zoo-goers may marvel at their bare skin and wrinkles, but scientists are more interested in the long lives of the pale, toothy and nearly hairless rodents known as naked mole rats. With lifespans of up to 31 years, naked mole rats live decades longer than would be expected based on their size. By comparison, mice live at most four years.
Tuesday, April 29, 2014 - 13:35
There have always been limitations to experiments with mice, but new technology, which allows scientists to replace mouse genes with human genes, could clear the way for new ground to be broken.
Tuesday, April 22, 2014 - 14:21
Deadly Australian snake venom is being used in an innovative new product to fast-track blood test results for seriously ill patients.
Thursday, April 17, 2014 - 14:56
With funding from the National Institutes of Health's National Institute of Aging, Cornell scientists are joining interdisciplinary collaborators from across the country to form the Canine Longevity Consortium – the first research network to study canine aging. It will lay the groundwork for a nationwide Canine Longitudinal Aging Study (CLAS), using dogs as a powerful new model system that researchers can study to find how genetic and environmental factors influence aging and what interventions might mitigate age-related diseases.
Wednesday, April 16, 2014 - 13:24
Schizophrenia is a severe disease for which there is still no effective medical treatment. In an attempt to understand exactly what happens in the brain of schizophrenic people, researchers from the Univ. of Southern Denmark have analyzed proteins in the brains of rats that have been given hallucinogenic drugs. This may pave the way for new and better medicines.
Monday, April 14, 2014 - 15:02
Thursday, April 10, 2014 - 15:28
Working with animal models, Duke University researchers and other scientists are making strides in growing muscle in the lab that not only repairs itself but exhibits strength similar to that of normal muscle.
Using lab-grown muscle could one day help people with certain muscle injuries, including accident victims with big gashes that lead to significant scar tissue. Engineering muscle that works like natural tissue could also accelerate the testing of new drugs: Scientists could use this tissue in place of animals.
Tuesday, April 8, 2014 - 14:38
Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation.
Monday, March 31, 2014 - 16:00
A new drug extracted from snail venom could provide a breakthrough in treating severe chronic pain without the risk of addiction and dangerous side effects, researchers have found. The venom - considered 100 times stronger than morphine - could lead to the development of a new class of oral drugs used to relieve nerve pain associated with injury, cancer, AIDS and other diseases.
Tuesday, March 18, 2014 - 14:00
While scientists know that a superfamily of genes inside olfactory receptors is responsible for our sense of smell – we still don’t know the mechanism behind the interpretation of odor molecules into a particular smell. A new study published in the journal Molecular Biology and Evolution has found a distinct gene pattern in the olfactory receptors of fruit-eating bats – potentially shedding some light on the mechanism behind our own sense of smell.
Wednesday, March 5, 2014 - 15:17
New research using fruit flies with Alzheimer’s protein finds that the disease doesn’t stop the biological clock ticking, but detaches it from the sleep-wake cycle that it usually regulates. Findings could lead to more effective ways to improve sleep patterns in those with Alzheimer’s.
Friday, February 28, 2014 - 14:48
Cancer of the pancreas is usually not detected
until it’s too late to cure. But precursor lesions that form in the
pancreas and its ducts can signal the disease before it strikes, and
when caught early enough, they can be prevented from progressing to become cancer.
A new study reports two breakthroughs in understanding those lesions and their role in pancreatic cancer: the development of the first mouse model that simulates a precursor lesion called intraductal papillary mucinous neoplasia (IPMN), and the identification of an enzyme, Brg1, that appears to help cause the formation of IPMN lesions while also suppressing another precursor lesion.
Wednesday, February 26, 2014 - 16:58
Colorado State University researchers are finding new ways to treat cancers in humans and pets, but they are doing it with a specimen not of those species: mice.
Monday, February 24, 2014 - 16:28
There is no biological cure for deafness—yet. We detect sound using sensory cells sporting microscopic hairlike projections, and when these so-called hair cells deep inside the inner ear are destroyed by illness or loud noise, they are gone forever. Or so scientists thought. A new study finds specific cells in the inner ear of newborn mice that regenerate these sensory cells—even after damage, potentially opening up a way to treat deafness in humans.
Friday, February 21, 2014 - 15:08
A new potential test for persistent Lyme disease uses an organism that's known to be good at picking up diseases: ticks.
Wednesday, February 19, 2014 - 14:15
Here’s another reason to love a dog: our best friend is helping scientists identify the genetic variations that may lead to obsessive-compulsive disorder (OCD) in people, according to new research. Because the human and canine versions are often similar — dogs may lick their paws to the point of injury while people may wash their hands until they bleed — the hope is these and other findings will help researchers develop new medications to treat the debilitating disorder.
Tuesday, February 18, 2014 - 15:08
Japanese researchers have confirmed for the first time an association in mice between a genetic mutation and the intractable autoimmune disease lupus erythematosus.
Friday, February 14, 2014 - 14:58
Temporary blindness heightens hearing and has potential as a therapy for some deaf people, animal research suggests.
Thursday, February 6, 2014 - 16:28
Adult zebrafish can replace bones when they lose a tail fin. Knowing how they do it might lead to better ways to treat bone fractures in people, researchers say.
Friday, January 31, 2014 - 15:23
An Irish scientist is trying to unravel the secrets of what we smell and how our noses evolved to aid survival. And she has come up with important answers by studying the sniffing skills of the bat.
Thursday, January 30, 2014 - 15:10